Biosynthetic Gene Cluster Database with Functional Annotations

Gene cluster information is based on MIBiG Version 4.0 (November 15th, 2024).

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Cluster list

MIBiG accession Biosynthetic class Organism name Main product Genes
BGC0000033PKSMicromonospora echinosporacalicheamicin74

Gene list

Product Protein ID UniProt Sequence similarity Function prediction
PDB hits SwissProt hits FUJISAN UNKAI
CalE6 AAM94792.1 Q8KNG3 96 74 21 11

Conserved domain list

PSSM ID Accession Short name E value PDB hits SwissProt hits
440391COG0626MetC3.00e-1789674
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]. Cystathionine beta-lyase/cystathionine gamma-synthase is part of the Pathway/BioSystem: Methionine biosynthesis

Functional site list

Site type Residues Source domain
Not found.

Structural domain list

Number of domains: 1

Predicted structure

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Developed by Tohru Terada1, Ryota Kobayashi1, Koutaro Ukai1, Yoshitaka Moriwaki1,2, Leow Chee Siang3, and Suguru Fujita1
1Computational Biology Laboratory, Department of Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, JAPAN
2Computational Drug Discovery and Design Laboratory, Medical Research Laboratory, Institute of Science Tokyo, JAPAN
3Graduate Faculty of Interdisciplinary Research Faculty of Engineering, Mechanical Engineering (Mechatronics), University of Yamanashi, JAPAN