Biosynthetic Gene Cluster Database with Functional Annotations

Gene cluster information is based on MIBiG Version 4.0 (November 15th, 2024).

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Cluster list

MIBiG accession Biosynthetic class Organism name Main product Genes
BGC0000541ribosomalPaenibacillus polymyxapaenicidin A7

Gene list

Product Protein ID UniProt Sequence similarity Function prediction
PDB hits SwissProt hits FUJISAN UNKAI
PaeA AFW17838.1 K7TS19 0 0 0 5
PaeF AFW17839.1 K7THP4 311 539 0 251
PaeE AFW17840.1 K7TA18 0 0 0 0
PaeG AFW17841.1 K7U6S7 0 0 1 0
PaeB AFW17835.1 K7TA14 3 3 0 0
PaeT AFW17836.1 K7U6S3 440 606 0 55
PaeC AFW17837.2 K7TE09 2 3 0 0

Protein interaction network in the cluster

Click to enlarge

Type Protein 1 Protein 2 ipSAE ipSAE_min ipTM
Homo PaeF (AFW17839.1) PaeF (AFW17839.1) 0.76 0.76 0.86
Hetero PaeF (AFW17839.1) PaeG (AFW17841.1) 0.75 0.69 0.84
Hetero PaeF (AFW17839.1) PaeE (AFW17840.1) 0.69 0.65 0.81
Homo PaeT (AFW17836.1) PaeT (AFW17836.1) 0.72 0.72 0.80
Homo PaeB (AFW17835.1) PaeB (AFW17835.1) 0.63 0.63 0.74
Hetero PaeA (AFW17838.1) PaeC (AFW17837.2) 0.63 0.14 0.73
Hetero PaeE (AFW17840.1) PaeG (AFW17841.1) 0.53 0.45 0.72
Homo PaeG (AFW17841.1) PaeG (AFW17841.1) 0.46 0.46 0.72
Hetero PaeA (AFW17838.1) PaeB (AFW17835.1) 0.61 0.10 0.63

Developed by Tohru Terada1, Ryota Kobayashi1, Koutaro Ukai1, Yoshitaka Moriwaki1,2, Leow Chee Siang3, and Suguru Fujita1
1Computational Biology Laboratory, Department of Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, JAPAN
2Computational Drug Discovery and Design Laboratory, Medical Research Laboratory, Institute of Science Tokyo, JAPAN
3Graduate Faculty of Interdisciplinary Research Faculty of Engineering, Mechanical Engineering (Mechatronics), University of Yamanashi, JAPAN